For a century we designed molecules and machines by prediction, and reality kept disagreeing. Anneal Labs uses DNA to build, measure, and evolve real structures, a million at a time.
It lets you place any component — a protein, an RNA, a metal atom, a sensor — exactly where you want it, programmably, at massively parallel scale.
Three of the hardest problems in sensing and measurement are the same missing capability in disguise: the inability to arrange molecular parts with nanometer precision, addressably, at scale.
We supply that capability once, and build real instruments on top of it — not reagents, not software, but integrated systems that see and measure single molecules at their own length scale.
DNA strands anneal into a designed structure — complementary sequences finding each other and settling into the shape we specified.
The system anneals toward the best structure — we synthesize a population, measure it, and let selection settle it toward the optimum.
DNA self-assembly fabricates sensing and imaging elements with atomically defined geometry — on the order of a trillion per synthesis.
Each element is read out at single-molecule resolution, turning a population of designs into a population of measured functions.
Selection drives the population toward the target, and the improved design feeds the next build. The loop closes.
DNA-defined pores with designed geometry and co-placed optical readout, resolving single-reaction events across many addressed channels.
Multiplexed molecular imaging probes and self-calibrating standards — and labeled nanoscale ground truth for AI imaging pipelines.
Deterministic placement of emitters and plasmonic elements into high-sensitivity sensors that conventional fabrication cannot build at scale.
DNA nanotechnology and bio-nano interfaces; wafer-scale and fractal DNA origami assembly.
Instrument development and the build-measure-evolve stack, from fabrication through readout.
Science program across single-molecule sensing, imaging, and selection-coupled assays.
If you work on DNA nanotechnology, single-molecule measurement, photonics, or molecular design — or you want to talk partnerships — we'd like to hear from you.
hello@anneal-labs.com